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The American Journal Of Clinical Nutrition, 77(1), 189-195

doi: 10.1007/s40618-022-01863-x 150 CaironiVPitoiaFTrimboliP

[1] Because the two act on different layers and pathways, using both tends to cover more of the aging picture than either alone

Since mitochondria are essential to our very existence, it is unsurprising that the effects of mitochondrial diseases can be severe, and sometimes lethal, spanning a wide-ranging spectrum of physiological and biochemical symptoms [1,3,4] (see Table 1 for examples)

With respect to the frequency of the severe deficiency, the variation between the different populations is notorious