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In addition to these factors, aging and obesity are also considered as endogenous risk factors
doi: 10.1126/science.6710156
The MASH mouse and hamster work published by Briand and colleagues in 2026 showed dose-dependent reductions in body weight, hepatic steatosis, and liver enzymes that exceeded what dual agonists produced in the same models (Briand et al., Obesity, 2026)
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