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These transgenic mice showed significantly reduced plasma testosterone levels (18% of normal)[124] and the IGF-I deficiency was correlated with an ultrastructural analysis of mutant Leydig cells revealing a significant developmental delay, with fewer and smaller Leydig cells than normal

This raised concerns about why Novo Nordisk isnt warning patients of such serious side effects and calls for more research

Diabetes-Related Hair Loss Type 2 diabetes itself may contribute to hair loss due to hormonal and circulatory changes that can affect hair health and growth

[DOI] [PMC free article] [PubMed] [Google Scholar] 3.ACG clinical guideline: epidemiology, risk factors, patterns of presentation, diagnosis, and management of colon ischemia (CI) Brandt LJ, Feuerstadt P, Longstreth GF, Boley SJ

Moving forward This research marks a significant step towards understanding weight loss medications' real-world use and outcomes