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The mechanism is obesity-specific in mice
Melatonin acts as an antioxidant agent that detoxifies accumulated reactive oxygen or nitrogen species or modulates the balance of pro-oxidant and anti-oxidant enzyme activities by inhibiting pro-oxidative enzymes like xanthine oxidase (XO) and activating antioxidant enzymes such as catalase (CAT), glutathione peroxidase (GPX), and superoxide dismutase (SOD) [15, 199]
Mechanism: Four Pathways, One Stack Each pathway maps to different receptors and partially distinct brain regions
Studies in models of spinal cord injury, traumatic brain injury, and peripheral nerve damage have shown protective effects
Warfarin-induced Stevens-Johnson syndrome with severe liver injury
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