Hsu et al used the TriNetX platform to study the association between semaglutide use and the incidence of NAION and found that it was associated with an increased risk in patients with diabetes at the 2-, 3-, and 4-year timepoints but not within 1 year of GLP-1 RA initiation
The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimers disease
Management of acute VPA intoxication is largely supportive
Rytelewski M, Harutyunyan K, Mallampati S, Zal AM, Baran N, Cavazos A, Butler JM, Konplev S, Marszalek J, Andreeff M , Vinogradov S, Zal T, Konopleva M
It combines phentermine, a stimulant that reduces your appetite, and topiramate, an anti-seizure medication that helps lower your appetite and make you feel fuller longer