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In terms of improving liver fibrosis in patients, semaglutide also demonstrated a trend toward providing clinical benefit to patients, with fewer NASH patients experiencing progression of liver fibrosis compared to placebo

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Furthermore, biological variables and pharmacological properties introduce additional complexity: Sampling Intensity: Accurate detection of pulse frequency requires high-frequency sampling (e.g., 5-minute intervals), as less-intensive methods can miss more than 50% of secretory events