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10.1016/j.appet.2005.01.002 137 WolfrumC.BesserD.LucaE.StoffelM

Cagrilintide is a long-acting amylin analog that works on the satiety pathway, the signal that tells your brain you are full and keeps you full, so appetite quiets and weight loss becomes sustainable rather than a constant fight

Women 40+: 0.51 lb per week with more fluctuation

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Few ideal properties of the drug that can be administered transdermally require that drug should be essentially non-irritating, dose should be preferably up to 20 mg or less and partition coefficient in octanol / water should be between 1 to 4