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After 56 weeks: Placebo group lost 1.2% of body weight Recommended dose (7.5/46 mg) group lost 7.8% of body weight Top dose (15/92 mg) group lost 9.8% of body weight The EQUIP trial enrolled 1,267 adults with class II and III obesity (BMI 35+)

Novo Nordisk press release, 2026 The Medicare GLP-1 Bridge launches July 1, 2026, giving eligible Medicare beneficiaries Wegovy weight-loss access at $50/month outside Part D not counting toward the $2,100 OOP cap

This phenomenon is sometimes described as hormesis, where a low dose of a compound has a beneficial effect while higher doses have the opposite impact

Indeed, knowledge of rate and patterns of induction of SLC22A4 expression in human tissues under different (e.g