Why GLP-1 Medications Cause Dry Mouth GLP-1s include: Semaglutide: Ozempic, Wegovy, Rybelsus Tirzepatide: Mounjaro, Zepbound Liraglutide: Saxenda Dulaglutide: Trulicity These medications influence multiple systems: Reduced appetite less chewing less saliva Hormonal changes that impact the salivary glands Altered digestion that affects hydration Lower overall fluid intake because you feel less thirsty For many users, dry mouth begins within a few doses
[70,71] One in vitro study demonstrated that chromodulin can increase insulin signaling by up to 800%
Honscheid A, Rink L, Haase H
"We have to weigh the risks and the benefits, and there are risks here because oftentimes you're dosing these medications at home," said Ellerin.
[18] In a 2019 study, a cohort of healthy male participants (n=11