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Mechanism of time-dependent inhibition of 5 alpha-reductase by delta 1-4-azasteroids: Toward perfection of rates of time-dependent inhibition by using ligand-binding energies.Biochemistry1995;34:13453-3459 85

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Central role of gut microbiota in IBD The normal gut microbiota is composed of various microorganisms, including bacteria, fungi, and viruses, which maintain gut homeostasis through metabolic products, immune regulation, and barrier function [91, 92]