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doi: 10.1016/S0140-6736(19)31149-3 255 HusainMBirkenfeldALDonsmarkMDunganKEliaschewitzFGFrancoDRet al

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A team led by Chia-Yen Jane Shu, a researcher at 23andMe, identified the genetic variants that cause these different drug responses by analyzing the genomes of 27,885 people who had taken GLP-1 medications

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In light of these translational obstacles for rAAV-PHP.eB and rAAV-PHP.B, one recent study produced AAV.CPP16 by inserting cell-penetrating peptides (CCPs) into the AAV9 capsid between Q588 and A589 amino acids [168]