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The average level of cAMP in GLP-1R KO mice was slightly lower than that in WT mice, but there was no significant difference between the two groups (Fig

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Thus, NADPH binding equilibrium is attained within the deadtime but influences the observed rate(s) of the first phase which fits to report a K NADPH of 7 0.9 M

J Cell Biochem 104:13561363 Kawanishi N, Sugimoto T, Shibata J, Nakamura K, Masutani K, Ikuta M, Hirai H (2006) Structure-based drug design of a highly potent CDK1, 2, 4, 6 inhibitor with novel macrocyclic quinoxalin-2-one structure