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Examples of approaches include conjugation to peptide carriers (e.g., to polylactic-co-glycolic acid [PLGA])

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Researchers can pharmacologically dissect these pathways using LY294002 (PI3K inhibitor) or U0126 (MEK inhibitor) to determine which downstream arm mediates a specific IGF-1 LR3 effect in their experimental system

Traction and traumatic hair loss Mechanical stress from tight hairstyles, repeated pulling, or physical trauma damages follicles