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doi: 10.1038/s41580-020-00314-w 13 WangDYinLChenRTanWLiangLXiangJet al

Many AOD9604 non-clinical studies showed no evidence of genetic damage or toxic effects

This drives the cell toward programmed cell death, especially mitochondria-dependent apoptosis [114]

Its approval was preceded by the outcomes of five phase III trials, which are summarized in Tables 1 and 2, each of which compare tirzepatide at 5 mg, 10 mg, and 15 mg to other medications comparing similar clinical endpoints