While GLP-1 medications may cause headaches in some users, some early research is exploring whether GLP-1related mechanisms could influence certain headache conditions, particularly those living with obesity-related migraine or a condition called idiopathic intracranial hypertension (IIH) (which causes chronic headaches due to elevated pressure around the brain)
Oral Wegovy : The first oral GLP-1 pill, with outcomes comparable to injections and the benefit of being a once-daily commitment
Shoshani O, Livne E, Armoni M, Shupak A, Berger J, Ramon Y, Fodor L, Gilhar A, Peled IJ, Ullmann Y
(1992) Identification of the active site residues in dipeptidyl peptidase IV by affinity labeling and site-directed mutagenesis
However, weight loss does not occur at a perfectly steady rate