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Nrf2-Related Signaling Pathway The nuclear factor erythrocyte 2-associated factor 2 (Nrf2) pathway is a major intracellular antioxidant stress pathway that plays an important role in oxidative stress response, cytoprotection and anti-inflammation in cells

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In the initial stage of carcinogenesis, ROS play a variety of roles, including mediating the activation of carcinogens, causing DNA damage, and interfering with responses to DNA damage [37,38,39]

4 mg every week for the whole study 4