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Creating dual-pathway growth hormone stimulation with 2.53 the peak GH amplitude of monotherapy

doi: 10.1007/s00709-010-0144-6

While the clinical phenotype observed in Papillon-Lefvre syndrome (PLS) necessitates careful monitoring of skin and periodontal health during DPP1 inhibition therapy, clinical trials have shown these adverse events occur at low frequencies (1%4%) and are predominantly mild to moderate in severity