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Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT

"Yes, that's why our abstract title asks, 'Too much of a good thing?' When I'm talking to patients about going on these drugs, they're like, 'I don't want to go on another medicine.' I say, 'You know what

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Clinical assessments were conducted every 3 months to evaluate efficacy, measured as percentage of total weight loss (%TWL), excess weight loss (%EWL), changes in BMI, and improvement in comorbidities, as well as tolerance, monitored for adverse effects including gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea) and discontinuation rates

W.et al (2001)