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Oral supplements, on the other hand, require ingestion and absorption through the digestive system

These nutrients are present in both seeds and leaves, though their distribution varies between the tissues (Narwade and Pinto, 2018

revealed that upregulated PDK1 activates epidermal growth factor receptor (EGFR) to facilitate the development of chemotherapy resistance (37)

Ethanol is oxidized to acetaldehyde by alcohol dehydrogenase I (ADH1), catalase (CAT) and/or cytochrome P450 2E1 (CYP2E1)

Looking forward, continued progress in nanomaterial design and synthesis, coupled with deeper insights into oral cancer pathophysiology, is expected to yield more efficient, safer, and highly precise nanoscale DDSs