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A patients response to chronic illness is unique based upon many factors ranging from emotional response to the disease, individual physical symptoms, immune response and the duration of the disease itself

Consequently, the elevated levels of free radicals can damage cellular structures, resulting in the accumulation of cytotoxic substances and ultimately leading to the death of substantia nigra cells, thereby triggering the onset of PD (Chittasupho et al., 2022)

Some customers report that the products did not meet expectations and did not work effectively

Addressing these challenges will require interdisciplinary approaches and sustained efforts to optimize the properties of NDBs and streamline their development pipeline for clinical use (Arciola et al., 2018