5 Integrated therapeutic approaches The pathophysiology of DKD is multifactorial, involving hyperglycemia, intraglomerular hypertension, chronic inflammation, oxidative stress, and progressive fibrosis
Forde and Roberts (2014) highlighted the contribution of GLRs to Ca 2+ flux during immune activation, emphasizing their importance as molecular hubs linking environmental cues with intracellular responses
A GrotheyKopetz S , Yaeger R, Van Cutsem E, Wasan H, Desai J, Ciardiello F, Yoshino T, Maharry K, Christy-Bittel J, Gollerkeri A, Tabernero J
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