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More clinical trials are needed before doctors can say whether GLP-1 medications have a direct role in cancer prevention or cancer treatment

These changes compromise granulosa cell support, impair meiotic progression, and accelerate ovarian aging, contributing to female infertility disorders such as polycystic ovary syndrome

Sulfonylurea discontinuation: Often possible and reduces hypoglycemia risk

Side Effect Profiles: What Clinical Evidence Actually Shows Comparative safety data from randomized controlled trials and real-world use reveals overlapping adverse event rates

Shared decision-making, incorporating current evidence, individual risk factors, and patient preferences, remains the cornerstone of appropriate tirzepatide use