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You should always stay well-hydrated when taking supplements, especially apple cider vinegar

Bozic J, Ahmed T, Ontsouka B, Fluckiger A-C, Diress A, Berthoud T, et al

Table 1 reveals the benefits of SGLT2 inhibitors combined with ACEI/ARBs

The roughly six percentage point difference between arms is what the data attribute to the drug in that population