glp-1 and gout Drugs May Raise the Risk of Osteoporosis Gout, Study Suggests GLP-1 for Weight Loss and

10.1016/s0140-6736(19)31271-1 64 RamracheyaR.ChapmanC.ChibalinaM.DouH.MirandaC.GonzlezA.et al (2018)

GLP-1 agonists (semaglutide, dulaglutide, liraglutide) are injectable or oral medications for type 2 diabetes and weight management that mimic natural GLP-1 hormone

For a long time, this medication was the only drug of its type, but in recent years, other GLP-1 agonists have been approved for both the treatment of diabetes and the treatment of obesity

Glucagon-Like Peptide 1-Based Therapies for the Treatment of Type 2 Diabetes Mellitus. Edited by David M Nathan and Katya Rubinow, UpToDate, Wolters Kluwer, 9 Nov

Retatrutide targets three different receptors: GLP-1 (helps regulate appetite and blood sugar) GIP (supports insulin response) Glucagon (affects energy use and fat metabolism) By targeting all three, the medication delays how fast your stomach digests food, lowers your appetite, and ultimately reduces how much food you eat