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Description

Melanoma skin cancers begin in melanocytes, which are in the deepest layers of the skin

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Each time a cell divides, telomeres become shorter, eventually leading to cellular senescence or apoptosis

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Senescent cells secrete increased levels of colony-stimulating factors, chemokines, and cytokines, e.g., GM-CSF, IL-6, IL-10, and TGF-, which can recruit and educate immune cells in aged tissues (see below)

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View this as part of a broader health approach

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Learn more about anaphylaxis

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