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This disruption occurs when NKG2D ligands such as ULBP and MICA are upregulated

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When administered intravenously to humans, functional magnetic resonance imaging (fMRI) revealed ghrelin increased the activity of the VTA and the regions it projects to (amygdala, striatum, hippocampus, cortex) when viewing pictures of food (Malik et al., 2008)

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