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Glutathione acts to protect the mitochondria of cells by eliminating free radicals [5]

13, 54 Our mechanistic investigations demonstrated that BSO+L-PAM induced significant increases in mitochondrial depolarization, cleavage of caspase-3, caspase-9, poly ADP ribose polymerase and DNA fragmentation

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The acquirement of T315I mutation causes tyrosine kinase inhibitors (TKI) resistance