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[80] used hydrophilic interaction liquid chromatography, electron ionization, and tandem mass spectrometry to target 612 metabolites in plasma, and identified disturbances across 20 biochemical metabolic pathways

Defect: C1 esterase inhibitor deficiency uncontrolled bradykinin activity

Additionally, keeping blood sugar stable reduces the risk of complications such as heart disease, which is more common for people with psoriatic arthritis and diabetes