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Body weight development of 47-week old male C57BL/6 J wildtype (WT) and Per-Gipr knockout (KO) mice treated daily with either vehicle, acyl-GLP-1 (10 nmolkg), or the combination of acyl-GLP-1 (10 nmol/kg) and a GIPR antagonist (1,500 nmol/kg) (n = 8 each group) (a)

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Targeting metabolic dysfunction and systemic inflammation offers a promising therapeutic approach for improving asthma control in individuals with obesity and T2DM