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Interest broadened sharply after Yang and colleagues (Cell, 2014) used targeted metabolomic profiling across twelve ferroptosis-inducing small molecules and found that glutathione depletion converges on inactivation of the selenoenzyme glutathione peroxidase 4, placing glutathione availability directly upstream of iron-dependent lipid peroxidation

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Andersson ML et al (2019): Butyrylcholinesterase deficiency and its clinical importance in anaesthesia: a systematic review

Drug Res 25:566-571, 1975

Public health initiatives promoting these approaches, alongside reduced intake of pro-inflammatory foods, represent a cost-effective strategy to lower the population-wide burden of obesity-related OA