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Temml C, Wehrberger C, Riedl C et al: Prevalence and correlates for interstitial cystitis symptoms in women participating in a health screening project

The authors declare no conflicts of interest

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The receptor exists in two splice variants: the active GHS-R1a, which binds acylated ghrelin, and the truncated GHS-R1b, which is pharmacologically inactive but can modulate the activity of 1a through heterodimerisation

Given that NACA was able to counteract the effects of the ACOX1 gain-of-function mutation, antioxidant treatment was considered for patient#1 during a severe disease flare