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Tirzepatide is MHRA-authorised as Mounjaro for type 2 diabetes and as Zepbound for weight management

For reconstitution in research workflows, bacteriostatic or sterile water is typically used

We kept the animals in the animal experiment center (SPF-grade) of Huazhong University of science and technology (22C2C, 12 h light/dark cycles, 40%60% humidity)

In two randomized controlled clinical trials, inulin ingestion did not change appetite, intestinal permeability, or levels of inflammatory biomarkers, but caused flatulence and soft stools (122, 124)

Harach T, Pols TWH, Nomura M, Maida A, Watanabe M, Auwerx J, et al