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GLP-1RAs have multiple pleiotropic actions, as they bind to GLP-1 receptors expressed in many human tissues including the pancreas, kidneys, lungs, heart, brain, and gastrointestinal tract [5, 6]

Previous studies have indicated that the association between DM and AF may involve mechanisms such as oxidative stress, inflammatory responses, abnormal energy metabolism, impaired cellular calcium handling, dysfunctional ion channels, and conduction disturbances (55)

Approximately 49% of investors are focusing on combination therapies integrating GLP-1 compounds

CPT 96401 covers non-hormonal antineoplastic (chemotherapy) drugs administered subcutaneously or intramuscularly, such as low-dose methotrexate for rheumatoid arthritis

doi:10.1155/2018/3763565 Wertenbruch T, Willenberg HS, Sagert C, et al