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Ann Intern Med (2007) 146(2):10415.10.7326/0003-4819-146-2-200701160-00005 247 FontanaLPartridgeLLongoVD

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More importantly, in combination with its NIR-II emission and GSH-specific activation characteristics, the probe LJ-GSH demonstrated promising capabilities for the precise localization of subcutaneous tumors and lung metastatic lesions, achieving the accurate removal of tumors with negative margins as small as 0.2 mm in diameter

Cumulative receptor saturation occurs when IGF-1 LR3 is dosed before prior clearance, producing an anabolic ceiling where additional IGF-1 binding no longer increases mTOR activation and instead drives glucose into adipose tissue

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