As depicted in Figure 3, we propose that the lactate-lactylation axis drives PH pathogenesis through five key mechanisms: PASMC proliferation, immune-inflammatory responses, pulmonary fibrosis, abnormal vasoconstriction, and PASMC ferroptosis
Overexpression of Glucose-6-phosphate Dehydrogenase Extends the Life Span of Drosophila melanogaster
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To view a copy of this licence, visit About this article Cite this article Chen, Y., Jiang, Z
The instrument performed a survey MS acquisition (TOFMS) from m/z 1201,250 (250 ms accumulation time), followed by MS/MS (high sensitivity mode) from m/z 801,500 on the 15 most intense precursor ions (excluded for 20 s after two occurrences) using information dependent acquisition with dynamic background subtraction