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Therapeutic interventions that target adipocyte lipolysis Targeting adipocyte lipolysis for reducing obesity and improving insulin resistance has been of therapeutic interest for decades now (222)

What to inject: 3.0 mL reconstitution: 51 units once weekly 2.0 mL reconstitution: 34 units once weekly 4.0 mL reconstitution: 68 units once weekly What to expect: Continued weight loss, often at a steady pace of 1 to 2 pounds per week for many researchers

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Ethics declarations Competing interests MV has within the last three years, served as consultant for Lundbeck, Eli Lilly and Johnson & Johnson

MA: Writing original draft, Writing review and editing