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10.3390/ijms21249682 133 SierraC.Lpez-SotoA.CocaA

Its zinc-chelating hydroxamate moiety inhibits several HDACs from different classes of Zn 2+ -dependent amidohydrolases, including HDAC1, HDAC2 and HDAC3 (class I) as well as HDAC6 (class IIb) 15

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Optimal doses specifically for disc repair have not been established through dose-finding studies