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and ii) non-steroidal anti-inflammatory drugs should be used locally, and uricotropin drugs should be used depending on the patient's condition

Every single module, delivering a specific monomer to the growing peptide, can be subdivided into conserved domains that carry all essential information for recognition, activation and modification of the substrate

This interaction with SIRT1, a key enzyme in cellular stress response and longevity, opens new research directions

11 , e1004060 (2015)

Coincidentally, the mutant CFTR is unable to also execute its cAMP-activated chloride channel function, which leads to the activation of the ENaC channel 31,32