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Nonetheless, this work has identified novel findings that support future studies to determine whether microbiome changes are contingent upon the combination of both NNMTi and LD switch and mediated through direct NNMTi-driven mechanisms or through indirect mechanisms such as weight or fat loss 8,13

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Upon this protein degradation, the free vitamin B12 will then proceed as above to be bound to an R-binder or transcobalamin I for entry into the duodenum

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