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Transcriptome and lipid Metabolomics-Based discovery: Glycyrrhizic acid alleviates tripterygium glycoside tablet-induced acute liver injury by regulating the activities of CYP and the metabolism of phosphoglycerides

Koch A, Konig B, Luci S, Stangl GI, Eder K: Dietary oxidised fat up regulates the expression of organic cation transporters in liver and small intestine and alters carnitine concentrations in liver, muscle and plasma of rats

No se han encontrado toxicidades importantes en estudios con ratas y perros

Its half-life is short (7 minutes) because it is rapidly cleaved by dipeptidyl peptidase-IV (DPP-IV) after residues 2-3