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As amylin and GLP-1 target different populations of neurons in the DVC 20 , this suggests that combination drug therapies affecting both systems may provide a greater magnitude and sustainable degree of weight loss compared to monotherapies due to a reduced likelihood of tachyphylaxis 21,22,23

Factors that limit results include inadequate protein intake, metabolic adaptation, medication non-compliance, and unrealistic timelines

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As magnesium helps break down sugars, it may help decrease insulin resistance and help manage the blood sugar levels in those with diabetes