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However, using a highly sensitive MethyLight method (Eads et al., 2000), the age-dependent increase in the methylation of NeuroD1 and NeuroD2 promoters was detected in the cortex (Siegmund et al., 2007)

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Therapeutically, paracetamol toxicity is counteracted with NAC prescription in patients with cystic fibrosis, in conditions with inspissated mucous secretions as pneumonia and bronchitis, and for patients with chronic obstructive pulmonary disease (COPD), as it does not increase the mucus volume, and for patients with nephropathy

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