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Loss of muscle mass, or sarcopenia, and the accompanying reduction in strength increases the risk of falls and their complications, and for many individuals the associated loss of physical, functional capacity leads to increasing difficulty in living independently

Baseline CSF levels of A1-42 in two studies (Siderowf et al., 2010

However, in this case, the patients usually do not show symptoms of metabolic acidosis or hemolytic anemia, and antioxidant therapies are ineffective ( Table 2 Clinical features and laboratory data corresponding to patients diagnosed with GSSD in China

Ethics statement The animal studies were approved by Institutional Animal Care and Use Committee of Yulin University (YULLPZ-2025-002)

doi: 10.1016/j.clindermatol.2016.10.007