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Novel biased GLP1 agonists described in the preclinical literature The first bespoke biased GLP1 agonist to be reported, P5, was obtained through an innovative strategy involving expression of single peptide sequences from an exendin4derived combinatorial peptide library, with peptides anchored to the cell surface via a flexible linker that allows autocrine activation of GLP1 receptors expressed in the same cell (Zhang et al., 2015)

ANS (8) : Refer Table 1 below: Table 1: Basic tests and reasons for monitoring drug actions NOTE : If the patient develops severe upper abdominal pain, nausea, or yellowing of the eyes while on these medications, it is necessary to consult a physician immediately

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