doi: 10.3390/compounds3010005 162 ZhangZLiXSangSMcClementsDJChenLLongJet al
TBK1 then phosphorylates and activates both the IRF3 pathway and the NF-B pathway, triggering the transcription of proinflammatory cytokines, antiviral chemokines, interferon-stimulated genes (ISGs), and type I IFNs
Acknowledgements This work was supported by the National Natural Science Foundation of China (82073313 to D.L.), the joint project of the State Administration of Traditional Chinese Medicine and Health Commission of Shandong Province (GZY-KJS-SD-2023-094), the Traditional Chinese Medicine Special Project of Binzhou Medical University Affiliated Traditional Chinese Medicine Hospital (2023ZYZX02) and the 2023 Qilu Biancang Traditional Chinese Medicine Talent Cultivation Project (to D.L.)
Subcellular Localizations [Isoform Mitochondrial]: Mitochondrion
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