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Pawlak R, Lester SE, Babatunde T

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Recent orthopaedic literature has emphasized that clinical exposure to BPC-157 has expanded far more rapidly than scientific validation, with published studies overwhelmingly consisting of preclinical models and only sparse human data (Vasireddi et al

This structural observation indicates that HGF I is the activating ligand that promotes c-MET dimerization and activation, whereas HGF II plays an auxiliary role that strengthens the interaction between HGF I and c-MET II

However, any combination should be approached thoughtfully with consideration of individual factors