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Once in circulation, GLP-1 has a short half-life (1 to 2 minutes) due to rapid degradation by the ubiquitous endogenous enzyme dipeptidyl peptidase-4 (DPP-4)

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GLP-1 supplements play a critical role in supporting health as appetite decreases and food intake becomes more limited

For long-term studies, it is highly recommended to aliquot the stock solution into single-use volumes in sterile microcentrifuge tubes and store them frozen at -20C or -80C

Combined with a healthy diet and exercise, Mounjaro can lead to patients losing up to 22.5% of their starting weight (after 72 weeks of treatment on a maintenance dose of 15mg)