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Locomotor functions were evaluated at 1 and 2 months post-HI with Catwalk and revealed significant exendin-4 and semaglutide induced improvements at 4 weeks ( C F ) and 8 weeks ( G J ) of age compared with the age-matched hypoxic-ischaemic group for various parameters: ( C , G ) run duration, ( D , H ) average speed, ( E , I ) regularity index, and ( F , J ) stride length (RF = right front, RH = right hind, LF = left front, LH = left hind) in saline controls (Control, 1 M n = 18, 2 M n = 15), HI non-treated (HINT, 1 M n = 16, 2 M n = 13), HI treated with Exendin-4 (Ex-4, 1 M n = 14, 2 M n = 12) and HI treated with Semaglutide (Sema, 1 M n = 21, 2 M n = 22)

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The market includes drugs like exenatide, liraglutide, semaglutide, lixisenatide, and albiglutide.

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