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by contrast, extended-release calcifediol reliably raised 25(OH)D and suppressed PTH in stage 34 CKD, but hard outcomes remain uncertain

Manufacturer-direct (LillyDirect, Novo's own subscription) and platform-aggregator (GoodRx) are both live now, competing for the same patient

Schauer I

Methods This retrospective cohort study was performed at two Swiss endocrine outpatient clinics (University Hospital Basel and Cantonal Hospital Olten)

In adjusted analyses, semaglutide reduced epigenetic aging across multiple second- and third-generation clocks, including PhenoAge ( 4.9 years/year, p = 0.004), PCGrimAge ( 3.1, p = 0.007), GrimAge V2 ( 2.3, p = 0.009), OMICmAge ( 2.2, p = 0.009), RetroAge ( 2.2, p = 0.030), and DunedinPACE ( 0.09 units, 9% slower, p = 0.01)