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This effect is compounded by the fact that fat loss is often disproportionate, with the face being one of the first areas to show volume depletion

Signs that point towards BAD include urgent, watery diarrhoea, symptoms worse after fatty meals, and frequent morning bowel movements

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November 2025: FDA approved expanded Zepbound (tirzepatide) indication for moderate-to-severe obstructive sleep apnea in adults with obesity, following SURMOUNT-OSA trial data showing 62.8% reduction in apnea-hypopnea index the first drug approval for sleep apnea treatment